Saturday 8 August 2015

KICK AND KILL HIV IN HIDING PLACES

The last two reports on this blog have dealt with the HIV virus in the blood stream and in the hiding places mainly in the lymph system.

The raped woman has to have ARV treatment early while the virus is still in the blood.

A woman having sex with an HIV positive man will have to have ARV treatment early so that the virus is killed in the blood stream. 

She may look forward to giving birth to a baby who is HIV negative.

Now there is a new development reported in the media. Up to now, the virus could be killed in the blood but not in the hiding places. So the person was always infected.

The ARV treatment killed in the blood only. If the sufferer stopped ARV treatment, the virus will cease to be dormant and burst out of the hiding places.

The Sunday Chronicle 9 August 2015 P.27.

The antiretroviral treatment has been the cornerstone of therapy. It kills the virus in the bloodstream but leaves the HIV reservoirs or hiding places untouched.

Experts say that new findings are interesting but have to be shown to be safe among patients. A strategy known as “kick and kill” is thought to be the key to curing infection.

The new drug would kick the dormant HIV in the hiding places and allow drugs to kill it. Once out in the blood, it can be killed.

A new report has said that the PEP005 is highly potent in reactivating latent HIV. It represents a new group of lead compounds for combating HIV.

Professor Sharon Lewin from the University of Melbourne said the results were interesting and marked an important advance in finding new compounds.

Comment: Professor Sharon Lewin has worked with Professor Jenny Hoy to produce a clinical book that has been the cornerstone of the AIDS Holistics awareness message in Papua New Guinea and the Pacific. Please click:

HIV Management in Australasia a guide for clinical care

www.som.uq.edu.au/media/418950/hiv_aus_guide.pdfDiscounted registration 

to the Annual Australasian HIV/AIDS Conference hosted by ASHM ... 

Editors: Jennifer Hoy, Sharon Lewin, Jeffrey J Post, Alan Street.


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